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Many people have brief episodes of depression and the majority of those people can obtain symptom relief from the more commonly prescribed SSRI antidepressants. Your treatment-refractory depression is different and so is Marplan.
Marplan's multi-transmitter effect (raising the levels of serotonin, norepinephrine, and dopamine in the brain) may represent a new treatment path your doctor can employ to successfully bring the symptoms of your depression under control.
In clinical studies with hundreds of patients, Marplan treatment was proven to be effective in 60% to 69%.*
* Meta-analysis of 12 studies of 434 depressed out-patients. Thase, ME, et al. (1995): MAOIs in the Contemporary Treatment of Depression. Neuropsychopharmacology 12(3):186.
Please see Full Prescribing Information including BOXED WARNINGS regarding increased risk of suicidality in children and adolescents. MAO-Inhibitors are contraindicated with certain drugs. Potential hypertensive crises may occur with foods that contain tyramine. As with all antidepressants, patients should be observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of treatment.
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